Neuromodulation is an effective treatment with a solid safety and efficacy record for multiple medical conditions. However, recently more attention has been placed on the economics of neuromodulation and the high upfront costs of the equipment; especially, in an environment of rising healthcare costs with significant patient cost-sharing. For patient therapy access to be maintained, it is important for healthcare providers and payers to understand the current cost-effectiveness data surrounding the treatment. Furthermore, physicians, manufacturers, payers, and organizational leadership will need to partner to maintain the economic viability of this technology in different sites of service. This session will provide an economic evaluation of the utilization of neuromodulation. Furthermore, techniques to enhance the economic viability will be discussed for different sites of service and selected equipment including rechargeable and non-rechargeable batteries.