Chronic pelvic pain is a debilitating condition that has a major impact on quality of life, health care resource utilization, and work productivity. It is the single most common reason for referral to women's health services and costs ~1 billion $ per year on its outpatient management. The etiology of chronic pelvic pain includes chronic pelvic pain syndrome [in women and men (formerly known as abacterial prostatitis)], pudendal neuralgia, nerve entrapment, post-surgical pain, cancer-related pain, and perineal/pelvic pain of unknown etiology. Chronic pelvic pain syndrome is often associated with irritable bowel syndrome, interstitial cystitis/painful bladder syndrome, endometriosis, or pelvic/adhesions. Treatment of chronic pelvic pain is multidimensional, including pelvic physical therapy, cognitive behavioral therapy, and various pharmacologic agent. However, pain often remains refractory despite this approach, and neuromodulation with Peripheral Nerve Stimulation can offer substantial pain relief in these cases. In addition to neural targets within the pelvis, there's growing evidence to suggest successful pain relief with neural targets outside of the pelvis.