Recently there has been renewed interest in modifying continuous stimulation programming to intermittent or cyclical stimulation with designated off times. Multiple reasons have been proposed for cycling including improving battery longevity while maintaining clinical outcomes. In addition, theoretical concerns have been proposed regarding the 'overdosing' of the spinal cord resulting in declining efficacy. This panel will highlight and explore clinical and basic science data surrounding cycling and the duty cycle in spinal cord stimulation. In addition, future trial designs will be proposed and discussed to further enhance our understanding of cycling and its appropriate deployment in programming parameters for spinal cord stimulation for the treatment of pain.