Open- vs. Closed-Loop Neurostimulation and Enabling Biomarkers

7:00 PM - 8:00 PM CST Friday, January 15

Neurostimulation of the human brain is a proven treatment for epilepsy and movement disorders, such as Parkinson's disease and essential tremor. Stimulation is typically done 'open-loop', with settings determined by a clinician and changed little between programming sessions. However, newer methods of tailoring ongoing stimulation to individual patient states have shown great promise for more effective and more efficient therapies. This session will review applications of open- and closed-loop stimulation, along with upcoming trends in both technologies.

Learning Objectives

Upon completion of this educational activity, participants should be able to:

  • Describe the differences between open- and closed-loop neurostimulation.
  • Explain how different biomarkers can be used to power closed-loop therapies.
  • Discuss currently available open- and closed-loop devices for treating neurological disorders.


John D. Rolston, MD PhD


Neurochemical Signals for Closed-Loop Treatments

Kendall H. Lee, MD PhD

Responsive vs. Continuous Stimulation for Epilepsy

John D. Rolston, MD PhD

Faculty and Presentations subject to change.