Neuromodulation Fundamentals: Effects on Neurons

4:00-5:30 PM Saturday, Jan. 14

Multiple lines of evidence suggest that spinal cord stimulation (SCS) modulates the activity of neurons in the spinal cord. This session will cover the latest research characterizing the effects of SCS waveforms on neurons and circuits in the spinal cord and higher centers, using a variety of approaches including animal studies and computational strategies.

Learning Objectives

Upon completion of this educational activity, participants should be able to:

  • Review the anatomy and physiology of spinal cord circuits engaged by SCS.
  • Describe computational techniques used to study the physiological effects of SCS.
  • Discuss the differential effects of SCS waveforms on neuron activity.
  • Discuss translatability issues with findings from animal studies.

SCS Effects on Spinal Dorsal Horn Networks

Steven A. Prescott, MD PhD

Burst and Tonic Stimulation Modulation of GABAergic Circuits

Glenn Franken, PhD

Neuromodulation Control of Spinal Function

Shawn Hochman, PhD

Differential Effects of SCS Waveforms

Andrei Sdrulla, MD PhD

Faculty subject to change.