Neuromodulation in Epilepsy: From Bench to OR to Outcomes

1:30 PM - 3:00 PM Friday, January 24

Neuromodulation treatments to treat drug-resistant epilepsy are expanding, including treatment paradigms that stimulate the brain directly to prevent or reduce seizures. With a growing number of options, several questions arise. What is the science behind brain stimulation in epilepsy, and how can animal models help us find new targets? What effects does neurostimulation have on brain networks beyond seizure control? How do we determine the best stimulation paradigm for an individual patient, and should it be open or closed loop? This session will examine how far we've come and where to go next in the rapidly growing field of epilepsy neuromodulation.

Learning Objectives

Upon completion of this educational activity, participants should be able to:

  • Describe the major brain stimulation options for drug-resistant epilepsy that are currently available and their differences.
  • Give an example of a new subcortical stimulation target that effects either seizures or cognition in epilepsy and possible network mechanisms behind it.
  • Discuss the advantages and disadvantages of open vs. closed loop stimulation.

Neuromodulation in Epilepsy: Neural Underpinnings and The Way Forward

Dario J. Englot, MD PhD

Targets and Mechanisms: Animal Studies of DBS in Epilepsy

Damian S. Shin, MSc PhD

Consciousness, Cognition, and Mood in Neurostimulation for Epilepsy

John D. Rolston, MD PhD

Case Presentations: Hippocampal Stimulation in Epilepsy

Arthur Cukiert, MD PhD

Case Presentations: RNS vs. DBS in Epilepsy

Chengyuan Wu, MD

Faculty and Presentations subject to change.